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GLYR1 antibody

Product Specifications

Background

May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) .

Synonyms

Cytokine-like nuclear factor N-PAC (NPAC) |3-hydroxyisobutyrate dehydrogenase-like protein|Glyoxylate reductase 1 homolog|Nuclear protein NP60|Nuclear protein of 60 kDa|Nucleosome-destabilizing factor (hNDF) |Putative oxidoreductase GLYR1|GLYR1|HIBDL|NDF|NP60|NPAC

Gene ID

84656

UniProt

Q49A26

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Cytokine-like nuclear factor n-pac

Target

GLYR1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

60 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF, IHC

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