GFM1 antibody
Product Specifications
Background
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
Synonyms
Elongation factor G, mitochondrial (EF-Gmt)|Elongation factor G 1, mitochondrial (mEF-G 1)|Elongation factor G1 (hEFG1)|GFM1|EFG|EFG1|GFM
Gene ID
85476
UniProt
Q96RP9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
G elongation factor, mitochondrial 1
Target
GFM1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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