CREB1 antibody
Product Specifications
Background
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Synonyms
Cyclic AMP-responsive element-binding protein 1|CREB-1|cAMP-responsive element-binding protein 1|CREB1|CREB
Gene ID
1385
UniProt
P16220
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
CAMP responsive element binding protein 1
Target
CREB1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IP, WB, IF, IHC, FC
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:3000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43-46 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IP, WB, IF, IHC, FC
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