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CREB1 antibody

Product Specifications

Background

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Synonyms

Cyclic AMP-responsive element-binding protein 1|CREB-1|cAMP-responsive element-binding protein 1|CREB1|CREB

Gene ID

1385

UniProt

P16220

Host

Rabbit

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

CAMP responsive element binding protein 1

Target

CREB1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IP, WB, IF, IHC, FC

Field of Research

Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:3000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

43-46 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IP, WB, IF, IHC, FC

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