APAF1 antibody
Product Specifications
Background
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Synonyms
Apoptotic protease-activating factor 1 (APAF-1) |APAF1|KIAA0413
Gene ID
317
UniProt
O14727
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Apoptotic peptidase activating factor 1
Target
APAF1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP, IF
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP, IF
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
