AP3B1 antibody

Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

AP-3 complex subunit beta-1|Adaptor protein complex AP-3 subunit beta-1|Adaptor-related protein complex 3 subunit beta-1|Beta-3A-adaptin|Clathrin assembly protein complex 3 beta-1 large chain|AP3B1|ADTB3A