ACACA antibody
Product Specifications
Background
ACACA (Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS) (PMID:19900410) . It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
Synonyms
Acetyl-CoA carboxylase 1 (ACC1) |Acetyl-Coenzyme A carboxylase alpha (ACC-alpha) |ACACA|ACAC|ACC1|ACCA
Gene ID
31
UniProt
Q13085
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Acetyl-Coenzyme A carboxylase alpha
Target
ACACA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
270 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
2223-2346aa
Curated Selection
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