Rafoxanide (Standard)
Rafoxanide (Standard) is the analytical standard of Rafoxanide. This product is intended for research and analytical applications. Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research[1][2][3].
Product Specifications
CAS Number
[22662-39-1]
UNSPSC
12352005
Target
Apoptosis; Oxidative Phosphorylation; p38 MAPK; Parasite; Raf; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/rafoxanide-standard.html
Solubility
DMSO : ≥ 31 mg/mL
Smiles
O=C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)C3=CC(I)=CC(I)=C3O
Molecular Formula
C19H11Cl2I2NO3
Molecular Weight
626.01
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
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