Tivanisiran (sodium)
Product Specifications
Product Name Alternative
SYL1001 (sodium)
UNSPSC Description
Tivanisiran sodium is a siRNA used for the study of dry eye disease. Tivanisiran sodium was designed to silence transient receptor potential vanilloid 1 (TRPV1) mRNA[1].
Target Antigen
TRP Channel
Type
Oligonucleotides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tivanisiran-sodium.html
Purity
92.22
Solubility
10 mM in H2O
Smiles
[Tivanisiran (sodium)]
Molecular Weight
12859.67
References & Citations
[1]Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to|[2]Javier Moreno-Montañés, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27(4):421-426.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132596A/Tivanisiran-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132596A/Tivanisiran-sodium-SDS-MedChemExpress.pdf
Clinical Information
Phase 3
CAS Number
1848239-71-3
Available Sizes
Curated Selection
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