Tivanisiran (sodium)

Tivanisiran sodium is a siRNA used for the study of dry eye disease. Tivanisiran sodium was designed to silence transient receptor potential vanilloid 1 (TRPV1) mRNA[1].

Product Specifications

CAS Number

[1848239-71-3]

Product Name Alternative

SYL1001 (sodium)

UNSPSC

12352208

Target

TRP Channel

Type

Oligonucleotides

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tivanisiran-sodium.html

Purity

96.85

Solubility

10 mM in H2O

Smiles

[Tivanisiran(sodium)]

Molecular Formula

C361H411N141O262Na36P36

Molecular Weight

12068.3 (free acid)

References & Citations

[1]Anne-Marie Bleau, et al. Development of tivanisiran, a topical siRNA designed to|[2]Javier Moreno-Montañés, et al. Tivanisiran, a novel siRNA for the treatment of dry eye disease. Expert Opin Investig Drugs. 2018 Apr;27 (4) :421-426.