Kinetin

Kinetin (N6-furfuryladenine) belongs to the family of N6-substituted adenine derivatives known as cytokinins, which are plant hormones involved in cell division, differentiation and other physiological processes. Kinetin has anti-aging effects[1].

Product Specifications

CAS Number

[525-79-1]

Product Name Alternative

6-Furfuryladenine; N6-Furfuryladenine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

SOD

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Kinetin.html

Concentration

10mM

Purity

99.76

Solubility

1M NaOH : 33.33 mg/mL (ultrasonic) |DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

C12=NC=NC(NCC3=CC=CO3)=C1N=CN2

Molecular Formula

C10H9N5O

Molecular Weight

215.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Hsiao G, et al. Inhibitory activity of kinetin on free radical formation of activated platelets in vitro and on thrombus formation in vivo. Eur J Pharmacol. 2003 Apr 4;465 (3) :281-7.|[2]Axelrod FB, et al. Kinetin improves IKBKAP mRNA splicing in patients with familial dysautonomia. Pediatr Res. 2011 Nov;70 (5) :480-3.|[3]Hims MM, et al. Therapeutic potential and mechanism of kinetin as a treatment for the human splicing disease familial dysautonomia. J Mol Med (Berl) . 2007 Feb;85 (2) :149-61.|[4]Griffaut B, et al. Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells. Int J Biol Macromol. 2004 Aug;34 (4) :271-5.