6-Chloropurine

6-Chloropurine is a building block in chemical synthesis. Intermediate in the preparation of 9-alkylpurines and 6-rnercaptopurine. Antitumor activities[1].

Product Specifications

CAS Number

[87-42-3]

Product Name Alternative

6-Chloro-9H-purine

UNSPSC

12352005

Hazard Statement

H302

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/6-Chloropurine.html

Purity

99.49

Solubility

DMSO : 27.5 mg/mL (ultrasonic) |H2O : 2.5 mg/mL (ultrasonic)

Smiles

ClC1=C2NC=NC2=NC=N1

Molecular Formula

C5H3ClN4

Molecular Weight

154.56

Precautions

H302

References & Citations

[1]Hwang IY, et al. Detection and mechanisms of formation of S- (6-purinyl) glutathione and 6-mercaptopurine in rats given 6-chloropurine. J Pharmacol Exp Ther. 1993 Jan;264 (1) :41-6.|[2]Sartorelli AC, et al. Comparative studies on the in vivo action of 6-chloropurine, 6-chloropurine ribonucleoside, and 6-chloro-9-ethylpurine on sarcoma 180 ascites cells. J Pharmacol Exp Ther. 1961 Oct;134:123-8.