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L-689502

L-689502 is a potent inhibitor of HIV-l protease with an IC50 of 1 nM.

Product Specifications

CAS Number

[138483-63-3]

UNSPSC

12352005

Target

HIV Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/L-689502.html

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)N[C@@H](CC1=CC=CC=C1)[C@@H](O)C[C@@H](CC2=CC=C(OCCN3CCOCC3)C=C2)C(N[C@@H]4[C@H](O)CC5=C4C=CC=C5)=O

Molecular Formula

C39H51N3O7

Molecular Weight

673.84

References & Citations

[1]Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181 (3) :1456-61.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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