CDK2

CDK2 is a member of the eukaryotic S/T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0/T0) in a protein substrate.

Product Specifications

CAS Number

[255064-79-0]

UNSPSC

12352209

Target

Ser/Thr Kinase

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/CDK2.html

Purity

98.61

Solubility

H2O

Smiles

NCCCC[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H]1N(C([C@H](CO)NC([C@H](C)NC([C@H](CC2=CNC=N2)NC([C@H](CC3=CNC=N3)N)=O)=O)=O)=O)CCC1)=O)=O

Molecular Formula

C35H57N15O9

Molecular Weight

831.92

References & Citations

[1]Bártová I, The mechanism of inhibition of the cyclin-dependent kinase-2 as revealed by the molecular dynamics study on the complex CDK2 with the peptide substrate HHASPRK. Protein Sci. 2005 Feb;14 (2) :445-51.