PF-03382792
Product Specifications
UNSPSC Description
PF-03382792 is a potent 5-HT4 partial agonist with a Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d. PF-03382792 can penetrate the brain. PF-03382792 produces moderate increases in cortical Ach in the rat prefrontal cortex[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf-03382792.html
Smiles
O=C(N1C(C(C)(C)C2=C1C=C(F)C=C2)=O)NCC3CCN(CC4(O)CCOCC4)CC3
Molecular Weight
433.52
References & Citations
[1]Michael A Brodney, et al.Identification of multiple 5-HT₄ partial agonist clinical candidates for the treatment of Alzheimer's disease. J Med Chem. 2012 Nov 8;55(21):9240-54.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18138/PF-03382792-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18138/
Clinical Information
Phase 1
CAS Number
1400811-63-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
LKU603532 96 Tests
Signaling Lymphocytic Activation Molecule Family, Member 2 (SLAMF2) Magnetic Luminex Assay Kit
Ask
View Details 
