Bethanechol

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].

Product Specifications

CAS Number

[674-38-4]

Product Name Alternative

Carbamyl-β-methylcholine

UNSPSC

12352211

Hazard Statement

H302-H312-H332

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Bethanechol.html

Solubility

10 mM in DMSO

Smiles

CC(OC(N)=O)C[N+](C)(C)C

Molecular Formula

C7H17N2O2

Molecular Weight

161.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Julia Yuen Hang Liu, et al. Acetylcholine exerts inhibitory and excitatory actions on mouse ileal pacemaker activity: role of muscarinic versus nicotinic receptors. Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319 (1) :G97-G107.|[2]M J Fregly, et al. Bethanechol-induced water intake in rats: possible mechanisms of induction. Pharmacol Biochem Behav. 1982 Oct;17 (4) :727-32.|[3]Inderbir S. Padda, et al. Bethanechol. Treasure Island (FL) : StatPearls Publishing; 2020 Jan-.