Pentosan Polysulfate

Pentosan Polysulfate is an orally bioavailable medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate also displays a potent and selective anti-HIV activity. Pentosan Polysulfatecan be used for the research of interstitial cystitis[1][2].

Product Specifications

CAS Number

[37300-21-3]

UNSPSC

12352005

Hazard Statement

H301-H311-H331-H341

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Pentosan_Polysulfate.html

Solubility

DMSO : < 1 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

[PentosanPolysulfate]

Molecular Weight

4000-6000

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501

References & Citations

[1]Schuchman EH, et al. Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses. PLoS One. 2013;8 (1) :e54459.|[2]Baba M, et al. Pentosan polysulfate, a sulfated oligosaccharide, is a potent and selective anti-HIV agent in vitro. Antiviral Res. 1988 Sep;9 (6) :335-43.|[3]Wu J, et al. Inhibition of inflammation by pentosan polysulfate impedes the development and progression of severe diabetic nephropathy in aging C57B6 mice. Lab Invest. 2011 Oct;91 (10) :1459-71.