K-Ras G12C-IN-2
K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor.
Product Specifications
CAS Number
[1629267-75-9]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/K-Ras-G12C-IN-2.html
Purity
99.21
Solubility
DMSO : ≥ 22 mg/mL
Smiles
ClC1=C(C2CC2)C=C(NCC(N3CCN(C4CN(C(C=C)=O)C4)CC3)=O)C(O)=C1
Molecular Formula
C21H27ClN4O3
Molecular Weight
418.92
References & Citations
[1]Pingda Ren, et al. Covalent inhibitors of kras g12c. WO2014152588A1
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
K-Ras
Curated Selection
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