1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
Product Specifications
UNSPSC Description
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells [1]. Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls[2].
Target Antigen
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/1-myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCC(OC[C@@H](O)COP(OCCN)(O)=O)=O
Molecular Weight
425.50
References & Citations
[1]Lee, J.M., Park, S.J., and Im, D.S. Lysophosphatidylethanolamine increases intracellular Ca2+ through LPA1 in PC-12 neuronal cells. Biochem. Biophys. Res. Commun. 461(2), 378-382 (2015).|[2]More, T.H., Bagadi, M., RoyChoudhury, S., et al. Comprehensive quantitative lipidomic approach to investigate serum phospholipid alterations in breast cancer. Metabolomics 13:3, (2017).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145547/1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145547/
Clinical Information
No Development Reported
CAS Number
123060-40-2
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