NA/Neuraminidase, Influenza A H1N1 (HEK293)

NA/Neuraminidase Protein is a receptor-destroying enzyme that cleaves terminal sialic acids from cellular receptors, potentially facilitating viral invasion of the upper airways by targeting sialic acid moieties on airway epithelial cell mucin. NA plays a pivotal role in viral propagation by catalyzing the removal of terminal sialic acid residues from both viral and cellular glycoconjugates. Moreover, the sialidase activity in late endosome/lysosome traffic appears to enhance virus replication. This product is an active extract, not a recombinant NA protein. It originates from cell lysates collected after expressing a DNA sequence encoding the Influenza A virus neuraminidase.