(R) -CSN5i-3
(R) -CSN5i-3 is the (R) -enantiomer of CSN5i-3. CSN5i-3 is a potent, selective and orally available inhibitor of CSN5[1].
Product Specifications
CAS Number
[2863607-74-1]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-csn5i-3.html
Purity
99.87
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C(F)F)=NN1C(C)C)NC2=CC(C3=CC=CC=C3)=C([C@H]4N5C(CCC[C@H]4O)=CN=C5)C=C2
Molecular Formula
C28H29F2N5O2
Molecular Weight
505.56
References & Citations
[1]Schlierf A, et al. Targeted inhibition of the COP9 signalosome for treatment of cancer. Nat Commun. 2016 Oct 24;7:13166.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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