Nicainoprol

Nicainoprol is a fast-sodium-channel blocking agent, which is a potent antiarrhythmic agent.

Product Specifications

CAS Number

[76252-06-7]

Product Name Alternative

RU-42924

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Nicainoprol.html

Purity

99.86

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N1CCCC2=C1C(OCC(O)CNC(C)C)=CC=C2)C3=CC=CN=C3

Molecular Formula

C21H27N3O3

Molecular Weight

369.46

Precautions

H302, H315, H319, H335

References & Citations

[1]Linz W, et al. Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril. Cardiovasc Drugs Ther. 1989 Dec;3 (6) :873-82.|[2]Martorana PA, et al. Effects of nicainoprol on reperfusion arrhythmia in the isolated working rat heart and on ischemia and reperfusion arrhythmia and myocardial infarct size in the anesthetized rat. Eur J Pharmacol. 1987 Nov 17;143 (3) :391-401.