Clerodendrin

Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor[1].

Product Specifications

CAS Number

[119738-57-7]

UNSPSC

12352005

Target

Interleukin Related

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/clerodendrin.html

Purity

99.66

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(O)=O)O)O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)C=C2OC(C5=CC=C(C=C5)O)=C1

Molecular Formula

C27H26O17

Molecular Weight

622.49

References & Citations

[1]Young KT, et, al. Inhibition of Interleukin-4 and β-Hexosaminidase Release in RBL-2H3 Cells by Compounds Isolated from Lobelia chinensis. 2021,27 (4) :251-6.