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CX-157

Product Specifications

UNSPSC Description

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3?ng/mL.

Target Antigen

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/CX-157.html

Solubility

10 mM in DMSO

Smiles

FC(F)(F)COC1=CC(OC2=CC(F)=CC=C2S3(=O)=O)=C3C=C1

Molecular Weight

348.27

References & Citations

[1]Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35(3):623-31.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100178/CX-157-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100178/

Clinical Information

Phase 2

CAS Number

205187-53-7

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