W-2429

W-2429 (NSC294836) is considerably more effective than acetylsalicylic acid in inhibiting carrageenan-induced edema and in reducing brewer's yeast-induced fever in rats[2].

Product Specifications

CAS Number

[37795-69-0]

Product Name Alternative

NSC294836

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/W-2429.html

Solubility

10 mM in DMSO

Smiles

O=C1N(OCC2)C2=NC3=C1C=CC=C3

Molecular Formula

C10H8N2O2

Molecular Weight

188.18

References & Citations

[1]Banerjee BN, et al. Toxicological investigation of 2,3-dihydro-9H-isoxazolo[3,2-b]quinazolin-9-one (W-2429) . Acuteand subacute toxicity in mice, rats and dogs. Arzneimittelforschung. 1977;27 (4) :793-801.|[2]Reisner DB, Ludwig BJ, Simon E, Dejneka T, Sofia RD. 2,3-Dihydro-9H-isoxazolo[3,2-b]quinazolin-9-ones and 3,4-dihydro- (1,2) -oxazino [3,2-b]quinazolin-10 (2H) -ones. Arzneimittelforschung. 1977;27 (4) :766-770.