Cyfluthrin

Cyfluthrin is a type II pyrethroid and has effects on various insects. Cyfluthrin is a modulator of Nav1.8 sodium channels by repetitive stimulation. Cyfluthrin can be applied in agriculture, veterinary, insecticide, pyrethroid and stored product[1][2].

Product Specifications

CAS Number

[68359-37-5]

UNSPSC

12352005

Hazard Statement

H300+H330, H362, H370, H410

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyfluthrin.html

Purity

99.52

Solubility

DMSO : ≥ 200 mg/mL

Smiles

O=C(C1C(C)(C)C1/C=C(Cl)\Cl)OC(C#N)C2=CC=C(F)C(OC3=CC=CC=C3)=C2

Molecular Formula

C22H18Cl2FNO3

Molecular Weight

434.29

Precautions

H300+H330, H362, H370, H410

References & Citations

[1]Jin-Sung Choi, et al.Structure-activity Relationships for the Action of 11 Pyrethroid Insecticides on Rat Na v 1.8 Sodium Channels Expressed in Xenopus Oocytes.Toxicol Appl Pharmacol. 2006 Mar 15;211 (3) :233-44|[2]María-Aránzazu Martínez, et al. Oxidative Stress and Related Gene Expression Effects of Cyfluthrin in Human Neuroblastoma SH-SY5Y Cells: Protective Effect of Melatonin. Environ Res. 2019 Oct;177:108579.