PD 127443

PD 127443 is an inhibitor of 5-lipoxygenase and cyclooxygenase. PD 127443 has anti-inflammatory activity[1].

Product Specifications

CAS Number

[121502-05-4]

UNSPSC

12352005

Target

COX; Lipoxygenase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/pd-127443.html

Smiles

OC1=C(C=C(C=C1C(C)(C)C)/C=C/C2=NNC(C)=C2)C(C)(C)C

Molecular Formula

C20H28N2O

Molecular Weight

312.45

References & Citations

[1]Schrier DJ, et al. The in vivo antiinflammatory effects of (E) -2,6-bis (1,1-dimethyl-ethyl) -4-[2- (5-methyl-1H-pyrazol-3-yl) ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase. Agents Actions. 1989 Jun;27 (3-4) :391-4.