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ARBK1 Colorimetric Cell-Based ELISA

The ARBK1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ARBK1 protein expression profile in cells. The kit can be used for measuring the relative amounts of ARBK1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ARBK1.

Product Specifications

Synonyms

Beta-adrenergic receptor kinase 1; Beta-ARK-1;2.7.11.15; G-protein coupled receptor kinase 2 ; GRK2 ; ADRBK1, BARK, BARK1

Gene Name

GRK2

UniProt

P25098

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in peripheral blood leukocytes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.

Molecular Weight

79574 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1696

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1696

Other Gene Names

Beta-adrenergic receptor kinase 1

Subcellular Location

Cytoplasm. Cell membrane.

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