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Anti-Phospho CNOT2 (Ser101) Antibody

Boster Bio Anti-Phospho CNOT2 (Ser101) Antibody (Catalog# P06400) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2

Gene Name

CNOT2

UniProt

Q9NZN8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human CNOT2 around the phosphorylation site of Ser101. Immunogen sequence location: 67-116

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes.

Applications

IHC-P, IF (paraffin), ELISA

Field of Research

Epigenetics and Nuclear Signaling, Mediator Complex, Transcription

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Sensitivity

<15pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.

Molecular Weight

59738 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=P06400

Product MSDS

https://www.bosterbio.com/msds?sku=P06400

Fragment

Rabbit IgG

Other Gene Names

CCR4-NOT transcription complex subunit 2

Subcellular Location

Cytoplasm. Nucleus.

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