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Anti-ZNRF2 Rabbit Monoclonal Antibody

Boster Bio Anti-ZNRF2 Rabbit Monoclonal Antibody catalog # M11505. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase ZNRF2;6.3.2.-; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2; ZNRF2; RNF202

Gene Name

E3 ubiquitin-protein ligase ZNRF2

UniProt

Q8NHG8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human ZNRF2

Clonality

Monoclonal

Clone

Clone: IGB-26

Tissue Specificity

Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney. .

Applications

WB, IHC

Field of Research

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ring Finger E3 Ligase, Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfer the ubiquitin to targeted substrates. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M11505

Product MSDS

https://www.bosterbio.com/msds?sku=M11505

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:100

Other Gene Names

ZNRF2

Subcellular Location

Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Cell junction, synapse, presynaptic cell membrane ; Peripheral membrane protein . Present in presynaptic plasma membranes in neurons.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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