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Anti-BAG2 Monoclonal Antibody

Boster Bio Anti-BAG2 Monoclonal Antibody catalog # M04933. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis; BBC3; PUMA

Gene Name

Bcl-2-binding component 3

UniProt

O95816

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human BAG2 Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.

Clonality

Monoclonal

Clone

Clone: AEOE-2

Tissue Specificity

Ubiquitously expressed. .

Applications

WB, ICC, IF

Field of Research

Metabolism, Pathways and Processes, Signal Transduction, Apoptosis, Cancer, Cell Biology, Intracellular, Cell Death, Metabolism Processes, Protein Trafficking, Chaperones, Invasion/Microenvironment, Apoptotic Markers

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M04933

Product MSDS

https://www.bosterbio.com/msds?sku=M04933

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>ICC/IF 1:50-1:200

Other Gene Names

BAG2

Subcellular Location

Mitochondrion . Localized to the mitochondria in order to induce cytochrome c release.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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