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Anti-Cytokeratin 16 KRT16 Rabbit Monoclonal Antibody

Boster Bio Anti-Cytokeratin 16 KRT16 Rabbit Monoclonal Antibody catalog # M03393. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 16; Cytokeratin-16; CK-16; Keratin-16; K16; KRT16; KRT16A

Gene Name

Keratin, type I cytoskeletal 16

UniProt

P08779

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Cytokeratin 16

Clonality

Monoclonal

Clone

Clone: EDC-11

Tissue Specificity

Expressed in the hair follicle, nail bed and in mucosal stratified squamous epithelia and, suprabasally, in oral epithelium and palmoplantar epidermis. Also found in luminal cells of sweat and mammary gland ducts.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Signal Transduction

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M03393

Product MSDS

https://www.bosterbio.com/msds?sku=M03393

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:50

Other Gene Names

KRT16

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065) . The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232) . .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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