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Anti-SPTA1 Rabbit Monoclonal Antibody

Boster Bio Anti-SPTA1 Rabbit Monoclonal Antibody catalog # M03376. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Calnexin; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90; CANX

Gene Name

Calnexin

UniProt

P02549

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human SPTA1

Clonality

Monoclonal

Clone

Clone: AFGF-19

Tissue Specificity

Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine. .

Applications

WB, IHC

Field of Research

Actin Binding Proteins, Actin, etc., Cardiovascular, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M03376

Product MSDS

https://www.bosterbio.com/msds?sku=M03376

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200

Other Gene Names

SPTA1

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065) . The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232) . .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

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