SQ 30774
SQ 30774 is a renin (renin) inhibitor. SQ 30774 has potent in vitro inhibitory effects in primates but not in rats, pigs, or dogs. And imidazolinol renin inhibitors also inhibit PRA and reduce arterial blood pressure in vivo[1].
Product Specifications
CAS Number
[121995-36-6]
UNSPSC
12352005
Target
Renin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sq-30774.html
Smiles
O=C([C@@H](N([C@H]([C@H](C1=NC=CN1)O)CC2CCCCC2)C([C@@H](NC(OC(C)(C)C)=O)CC3=CC=CC=C3)=O)CC4=CNC=N4)N
Molecular Formula
C32H45N7O5
Molecular Weight
607.74
References & Citations
[1]Pharmacology of novel imidazole alcohol inhibitors of primate renin
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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