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Anti-Fascin Monoclonal Antibody

Boster Bio Anti-Fascin Monoclonal Antibody catalog # M02147-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Excitatory amino acid transporter 1; Sodium-dependent glutamate/aspartate transporter 1; GLAST-1; Solute carrier family 1 member 3; SLC1A3; EAAT1, GLAST, GLAST1

Gene Name

Excitatory amino acid transporter 1

UniProt

Q16658

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Fascin Promotes cross-linkage of parallel actin filaments during the formation of cell protrusions (lamellipodia and filopodia), and therefore plays an important role in regulating cell migration. It has been reported that fascin may also regulate filopodia formation by a mechanism independent of its actin-bundling functions, though less is known about this mechanism of action.

Clonality

Monoclonal

Clone

Clone: ADOA-6

Tissue Specificity

Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M02147-1

Product MSDS

https://www.bosterbio.com/msds?sku=M02147-1

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:5000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:50<br>FC 1:100

Other Gene Names

FSCN1

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

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