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Anti-IDE/Insulysin Rabbit Monoclonal Antibody

Boster Bio Anti-IDE/Insulysin Rabbit Monoclonal Antibody catalog # M01358. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Insulin-degrading enzyme;3.4.24.56; Abeta-degrading protease; Insulin protease; Insulinase; Insulysin; IDE

Gene Name

Insulin-degrading enzyme

UniProt

P14735

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human IDE

Clonality

Monoclonal

Clone

Clone: AOOB-9

Tissue Specificity

Expressed in endoderm, intestinal epithelial cells and in most extraembryonic tissues. .

Applications

WB, IHC

Field of Research

Alzheimer's Disease, Atherosclerosis, Cancer, Cardiovascular, Cell Biology, Diabetes, Diabetes-associated, Growth Factors/Hormones, Heart Disease, Metabolism, Metalloprotease, Neurodegenerative Disease, Neurology Process, Neuroscience, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01358

Product MSDS

https://www.bosterbio.com/msds?sku=M01358

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:100

Other Gene Names

IDE

Subcellular Location

Cytoplasm. Cell membrane. Secreted . Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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