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Anti-Cytokeratin 18 KRT18 Rabbit Monoclonal Antibody

Boster Bio Anti-Cytokeratin 18 KRT18 Rabbit Monoclonal Antibody catalog # M01357-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; PIG46

Gene Name

Keratin, type I cytoskeletal 18

UniProt

P05783

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Cytokeratin 18

Clonality

Monoclonal

Clone

Clone: HB-11

Tissue Specificity

Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Intermediate Filaments, Microtubules, Signal Transduction, Structures, Tumor Associated

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01357-1

Product MSDS

https://www.bosterbio.com/msds?sku=M01357-1

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:50

Other Gene Names

KRT18

Subcellular Location

Cytoplasm, perinuclear region. Nucleus, nucleolus.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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