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Anti-Chromogranin A / CHGA (Neuroendocrine Marker) Monoclonal Antibody

Boster Bio Anti-Chromogranin A / CHGA (Neuroendocrine Marker) Monoclonal Antibody (Catalog # M01256) . Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human, Monkey, Pig, Mouse, Rat.

Product Specifications

Background

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Synonyms

Chromogranin-A; CgA; Pituitary secretory protein I; SP-I; Vasostatin-1; Vasostatin I; Vasostatin-2; Vasostatin II; EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; Catestatin ; SL21 ; AL-11; GV-19; GR-44; ER-37; GE-25 ; Serpinin-RRG; Serpinin; p-Glu serpinin precursor; CHGA

Gene Name

CHGA

UniProt

P10645

Host

Mouse

Reactivity

Human, Monkey, Pig, Mouse, Rat

Immunogen

Human pheochromocytoma

Clonality

Monoclonal

Clone

Clone: Clone: SPM339

Tissue Specificity

GE-25 is found in the brain. .

Applications

Flow Cytometry, IF, IHC

Field of Research

Neuron Marker, Neuroscience, Signal Transduction, Tags & Cell Markers, Tumor Associated, Tumor Biomarkers

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.

Molecular Weight

50688 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01256

Product MSDS

https://www.bosterbio.com/msds?sku=M01256

Fragment

IgG1, kappa

Other Gene Names

Chromogranin-A

Subcellular Location

Finely granular cytoplasmic

Curated Selection

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