Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody

Boster Bio Anti-RING2 / RING1B / RNF2 Rabbit Monoclonal Antibody catalog # M01209. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Vinculin; Metavinculin; MV; VCL

Gene Name

Vinculin

UniProt

Q99496

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human RING2 / RING1B / RNF2 E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.

Clonality

Monoclonal

Clone

Clone: AEDC-18

Tissue Specificity

Metavinculin is muscle-specific.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

2339, Chromatin Remodeling, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Actin filament (F-actin) -binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01209

Product MSDS

https://www.bosterbio.com/msds?sku=M01209

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:50

Other Gene Names

RNF2

Subcellular Location

Cytoplasm, cytoskeleton . Cell junction, adherens junction . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, focal adhesion . Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity) . Colocalizes with LIMD1 in the focal adhesions. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Mouse Monoclonal HSD17B8 Antibody (OTI2E12) [Allophycocyanin]
NBP2-71350APC 0.1 mL

Mouse Monoclonal HSD17B8 Antibody (OTI2E12) [Allophycocyanin]

Ask
View Details
NT5C2, Human
HY-P703300 Inquire

NT5C2, Human

Ask
View Details
Goat anti-Rabbit IgA Heavy Chain Antibody DyLight 488 Conjugated
MBS3900363-01 0.5 mg

Goat anti-Rabbit IgA Heavy Chain Antibody DyLight 488 Conjugated

Ask
View Details
Goat anti-Rabbit IgA Heavy Chain Antibody DyLight 488 Conjugated
MBS3900363-02 5x 0.5 mg

Goat anti-Rabbit IgA Heavy Chain Antibody DyLight 488 Conjugated

Ask
View Details
Mouse Monoclonal OGFOD1 Antibody (OTI1D9) [Allophycocyanin/Cy7]
NBP2-73145APCCY7 0.1 mL

Mouse Monoclonal OGFOD1 Antibody (OTI1D9) [Allophycocyanin/Cy7]

Ask
View Details
G-Protein Coupled Receptor 20 (GPR20) Antibody
abx029913-01 80 µL

G-Protein Coupled Receptor 20 (GPR20) Antibody

Ask
View Details