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Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody

Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148) . Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Synonyms

CD27 antigen; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD27; CD27; TNFRSF7

Gene Name

CD27

UniProt

P26842

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human CD27 protein

Clonality

Monoclonal

Clone

Clone: Clone: LPFS2/1611

Tissue Specificity

Found in most T-lymphocytes.

Applications

ELISA, Flow Cytometry, IF, IHC

Field of Research

Adaptive Immunity, Cancer, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage, TNF Superfamily, Tumor Immunology

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Molecular Weight

29137 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01148

Product MSDS

https://www.bosterbio.com/msds?sku=M01148

Fragment

IgG1, kappa

Other Gene Names

CD27 antigen

Subcellular Location

Cell Surface

Curated Selection

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