Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CD41 ITGA2B Rabbit Monoclonal Antibody

Boster Bio Anti-CD41 ITGA2B Rabbit Monoclonal Antibody catalog # M01102. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD41; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; ITGA2B; GP2B, ITGAB

Gene Name

Integrin alpha-IIb

UniProt

P08514

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD41

Clonality

Monoclonal

Clone

Clone: AAGH-9

Tissue Specificity

Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U-937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.

Applications

WB, IHC

Field of Research

Angiogenesis, Cardiovascular, Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Platelets, Signal Transduction, Stem Cells

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01102

Product MSDS

https://www.bosterbio.com/msds?sku=M01102

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:1000<br>IHC 1:50-1:200

Other Gene Names

ITGA2B

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Dkk-2 CT (Dickkopf Related Protein-2, Dickkopf-2, DKK-2, UNQ682/PRO1316) (MaxLight 750)
MBS6472601-01 0.1 mL

Dkk-2 CT (Dickkopf Related Protein-2, Dickkopf-2, DKK-2, UNQ682/PRO1316) (MaxLight 750)

Ask
View Details
Dkk-2 CT (Dickkopf Related Protein-2, Dickkopf-2, DKK-2, UNQ682/PRO1316) (MaxLight 750)
MBS6472601-02 5x 0.1 mL

Dkk-2 CT (Dickkopf Related Protein-2, Dickkopf-2, DKK-2, UNQ682/PRO1316) (MaxLight 750)

Ask
View Details
RT1-Da Rat shRNA Lentiviral Particle (Locus ID 294269)
TL701130V 500 µL Each

RT1-Da Rat shRNA Lentiviral Particle (Locus ID 294269)

Ask
View Details
Human LYN Protein, GST Tag
E40KMPH2377 20ug

Human LYN Protein, GST Tag

Ask
View Details
Olfr978 CRISPR Activation Plasmid (m2)
sc-435173-ACT-2 20 µg

Olfr978 CRISPR Activation Plasmid (m2)

Ask
View Details
Human IL-17 F (Interleukin 17F) QuickTest ELISA Kit
QT-EH4328 96 Tests

Human IL-17 F (Interleukin 17F) QuickTest ELISA Kit

Ask
View Details