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Anti-CD79a Monoclonal Antibody

Boster Bio Anti-CD79a Monoclonal Antibody catalog # M01047-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Caspase-7; CASP-7;3.4.22.60; Apoptotic protease Mch-3; Cysteine protease LICE2; Caspase-7 subunit p20; Caspase-7 subunit p11; Casp7; Lice2, Mch3

Gene Name

Caspase-7

UniProt

P11912

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD79a Antigen binding precedes formation of the CD79A and CD79B heterodimer and subsequent activation of receptor associated kinases. CD79A is a marker for B-lineage lymphoblastic leukemia; mutations in the corresponding mb-1 gene are responsible for abnormally low levels of functional B cell receptors in some cases of chronic B-cell lymphocytic leukemia.

Clonality

Monoclonal

Clone

Clone: ADOO-3

Tissue Specificity

Highly expressed in heart, lung, liver and kidney. Low levels in spleen, skeletal muscle and testis. No expression in the brain.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Adaptive Immunity, B Cells, Cancer, Hematopoietic Progenitors, Immunoglobulins, Immunology, Lymphoid, Receptors, Stem Cells, Tumor Immunology

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Overexpression promotes programmed cell death (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01047-1

Product MSDS

https://www.bosterbio.com/msds?sku=M01047-1

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:5000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:30

Other Gene Names

CD79A

Subcellular Location

Cytoplasm.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

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