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Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody

Boster Bio Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody catalog # M00595. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Histone deacetylase 6; HD6;3.5.1.98; HDAC6; KIAA0901; JM21

Gene Name

Histone deacetylase 6

UniProt

Q9UBN7

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human HDAC6

Clonality

Monoclonal

Clone

Clone: HEE-8

Tissue Specificity

T-cells and endothelial cells.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Acetylation, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Signaling Pathways, Stem Cells

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) . Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00595

Product MSDS

https://www.bosterbio.com/msds?sku=M00595

Fragment

Rabbit IgG

Applications Notes

WB 1:5000-1:20000<br>IHC 1:50-1:200<br>ICC/IF 1:100-1:500<br>IP 1:50

Other Gene Names

HDAC6

Subcellular Location

Nucleus. Cytoplasm. Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules.

Protein Name

T-cell surface glycoprotein CD4

Curated Selection

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