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Anti-SKP2 Monoclonal Antibody

Boster Bio Anti-SKP2 Monoclonal Antibody catalog # M00544. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

G1/S-specific cyclin-E1; CCNE1; CCNE

Gene Name

G1/S-specific cyclin-E1

UniProt

Q13309

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human SKP2 Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription.

Clonality

Monoclonal

Clone

Clone: ADCE-19

Tissue Specificity

Highly expressed in testis and placenta. Low levels in bronchial epithelial cells. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cardiogenesis, Cardiovascular, Cell Biology, F Box E3 Ligase, Oncoproteins, Oncoproteins/Suppressors, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Transcription Factors/Regulators, Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Essential for the control of the cell cycle at the G1/S (start) transition. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00544

Product MSDS

https://www.bosterbio.com/msds?sku=M00544

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>FC 1:50

Other Gene Names

SKP2

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

Curated Selection

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