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Anti-Gli1 Rabbit Monoclonal Antibody

Boster Bio Anti-Gli1 Rabbit Monoclonal Antibody catalog # M00527. Tested in WB application. This antibody reacts with Human.

Product Specifications

Synonyms

Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; GLI1; GLI

Gene Name

Zinc finger protein GLI1

UniProt

P08151

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Gli1

Clonality

Monoclonal

Clone

Clone: GCG-7

Tissue Specificity

Testis, myometrium and fallopian tube. Also expressed in the brain with highest expression in the cerebellum, optic nerve and olfactory tract. .

Applications

WB

Field of Research

Cancer, Domain Families, Epigenetics and Nuclear Signaling, Krueppel Like Factor, Neural Signal Transduction, Neurology Process, Neuroscience, Nuclear, Oncoproteins/Suppressors, Signaling Pathways, Stem Cells, Transcription, Tumor Suppressors, Zinc Finger

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00527

Product MSDS

https://www.bosterbio.com/msds?sku=M00527

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:1000

Other Gene Names

GLI1

Subcellular Location

Cytoplasm. Nucleus. Tethered in the cytoplasm by binding to SUFU. Activation and translocation to the nucleus is promoted by interaction with STK36. Phosphorylation by ULK3 may promote nuclear localization. Translocation to the nucleus is promoted by interaction with ZIC1.

Protein Name

T-cell surface glycoprotein CD4

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