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Anti-ROC1 Monoclonal Antibody

Boster Bio Anti-ROC1 Monoclonal Antibody catalog # M00524. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Signal transducer and activator of transcription 6; IL-4 Stat; STAT6

Gene Name

Signal transducer and activator of transcription 6

UniProt

P62877

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human ROC1 E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair.

Clonality

Monoclonal

Clone

Clone: ADCI-18

Tissue Specificity

Plasma. Synthesized by the fetal liver and yolk sac.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Cell Biology, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, SCF Complex E3 Ligase, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00524

Product MSDS

https://www.bosterbio.com/msds?sku=M00524

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200<br>IP 1:50<br>FC 1:100

Other Gene Names

RBX1

Subcellular Location

Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.

Protein Name

T-cell surface glycoprotein CD4

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