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Anti-AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody

Boster Bio Anti-AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Monoclonal Antibody (Catalog # M00522) . Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human, Monkey, Dog, Pig.

Product Specifications

Background

This monoclonal antibody recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) . This monoclonal antibody is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Synonyms

Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; AFP; HPAFP

Gene Name

AFP

UniProt

P02771

Host

Mouse

Reactivity

Human, Monkey, Dog, Pig

Immunogen

Alpha feto protein (AFP) Purified from serum of a hepatoma patient

Clonality

Monoclonal

Clone

Clone: Clone: SPM334

Tissue Specificity

Plasma. Synthesized by the fetal liver and yolk sac.

Applications

Flow Cytometry, IF, IHC

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.

Molecular Weight

68678 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00522

Product MSDS

https://www.bosterbio.com/msds?sku=M00522

Fragment

IgG2a, kappa

Other Gene Names

Alpha-fetoprotein

Subcellular Location

Cytoplasmic

Curated Selection

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