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Anti-MCM2 Rabbit Monoclonal Antibody

Boster Bio Anti-MCM2 Rabbit Monoclonal Antibody catalog # M00374. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DNA replication licensing factor MCM2;3.6.4.12; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28; MCM2; BM28, CCNL1, CDCL1, KIAA0030

Gene Name

DNA replication licensing factor MCM2

UniProt

P49736

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human MCM2

Clonality

Monoclonal

Clone

Clone: BCA-13

Tissue Specificity

Highly expressed in substantia nigra. .

Applications

WB, IHC, ICC, IF

Field of Research

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00374

Product MSDS

https://www.bosterbio.com/msds?sku=M00374

Fragment

Rabbit IgG

Applications Notes

WB 1:1000-1:5000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200

Other Gene Names

MCM2

Subcellular Location

Nucleus .

Protein Name

T-cell surface glycoprotein CD4

Curated Selection

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