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Anti-FoxO3a Rabbit Monoclonal Antibody

Boster Bio Anti-FoxO3a Rabbit Monoclonal Antibody catalog # M00252-1. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1, FOXO3A

Gene Name

Forkhead box protein O3

UniProt

O43524

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human FoxO3a

Clonality

Monoclonal

Clone

Clone: ACA-6

Tissue Specificity

Ubiquitous. .

Applications

WB, IHC, ICC, IF

Field of Research

Apoptosis, Associated Proteins, Cancer, Cell Biology, Co-Activators/Co-Repressors, Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Hypoxia, Intracellular, Metabolism, Metabolism Processes, Nuclear Receptors, Nuclear Signaling Pathways, Oncoproteins, Oncoproteins/Suppressors, Pathways and Processes, Transcription, Transcription Factors

Purification

Affinity-chromatography

Concentration

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Function

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00252-1

Product MSDS

https://www.bosterbio.com/msds?sku=M00252-1

Fragment

Rabbit IgG

Applications Notes

WB 1:500-1:2000<br>IHC 1:50-1:200<br>ICC/IF 1:50-1:200

Other Gene Names

FOXO3

Subcellular Location

Cytoplasm, cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.

Protein Name

P2X purinoceptor 1

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