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Anti-HLA-Aw32 & HLA-A25 (MHC I) Monoclonal Antibody

Boster Bio Anti-HLA-Aw32 & HLA-A25 (MHC I) Monoclonal Antibody (Catalog # M00194) . Tested in Flow Cytometry, IF, IHC applications. This antibody reacts with Human.

Product Specifications

Background

This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This monoclonal antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.

Synonyms

HLA class I histocompatibility antigen, B-7 alpha chain; MHC class I antigen B*7; HLA-B; HLAB

Gene Name

HLA-A

UniProt

P01889; P30443; P30499

Host

Mouse

Reactivity

Human

Immunogen

Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10

Clonality

Monoclonal

Clone

Clone: Clone: SPM417

Applications

Flow Cytometry, IF, IHC

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

Involved in the presentation of foreign antigens to the immune system.

Molecular Weight

40460 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00194

Product MSDS

https://www.bosterbio.com/msds?sku=M00194

Fragment

IgG2a, kappa

Other Gene Names

HLA class I histocompatibility antigen, B-7 alpha chain

Subcellular Location

Cell Surface

Curated Selection

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